Nigericin
Nigericin is a potent microbial toxin and potassium ionophore that can induce pyroptosis. It induces a net decrease in intracellular potassium. This is critical for the oligomerization of the NLRP3 inflammasome and caspase-1 activation in pyroptosis.
Nigericin
Nigericin is a potent microbial toxin and potassium ionophore that can induce pyroptosis. It induces a net decrease in intracellular potassium. This is critical for the oligomerization of the NLRP3 inflammasome and caspase-1 activation in pyroptosis.
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Description
Nigericin is a potent microbial toxin and potassium ionophore that can induce pyroptosis. It induces a net decrease in intracellular potassium. This is critical for the oligomerization of the NLRP3 inflammasome and caspase-1 activation in pyroptosis.
